Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

Join Discover

Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Iterative Health

Healthcare

Iterative Health

Iterative Health is pioneering the use of artificial intelligence-based precision medicine in gastroenterology (GI), with the aim of helping to optimize clinical trials investigating treatment of inflammatory bowel disease (IBD). We use advanced machine learning and computer vision to interpret endoscopic images along with other types of data, helping clinicians to better assess patients with potential GI problems. This gives practitioners enhanced capabilities in the detection, annotation, disease scoring and treatment of GI related diseases. Iterative Health is initially applying these advances towards standardizing disease severity characterization for inflammatory bowel disease. Ultimately, the company aims to establish more meaningful endpoints to serve as better predictors of both therapeutic response and disease outcomes. The company is headquartered in Cambridge, Massachusetts.

Details

Overjet

Overjet is pioneering the next era of dentistry. Modern DSOs and insurance companies are realizing the clinical and operational value of innovative technologies and moving towards smart operations that leverage artificial intelligence. Guided by a patient-centric AI, Overjet’s FDA-cleared platform offers more data points in x-rays than previously possible. It integrates with major practice management and imaging systems to guide clinicians to arrive at precise & accurate diagnostic decisions, better care and patient outcomes that drive dentistry forward. With data-driven diagnoses being the key to success, Overjet enables clinicians to achieve higher clinical accuracy, precision, and consistency. When dentists see objective confirmation of a diagnosis they made, they feel more confident, and patients know they can trust their doctors. Building on formative experiences with MIT and Harvard School of Dental Medicine, Overjet was founded on the vision to enhance clinical decision-making to improve oral health. Every day, some of the largest DSOs, dental groups, and insurance companies rely on accurate information provided by Overjet to deliver care and services.

Hydrow

Healthcare

Hydrow

New to the market, fast-growing, incredibly innovative, and already recognized as one of the Boston Globe’s Top Places to Work, Hydrow is the Live Outdoor Reality (LOR)™ rowing machine that delivers on-water experiences at home with workouts led by world-class athletes. Engaging twice as many muscles as cycling (86%, in fact), Hydrow’s interactive technology delivers challenging virtual workouts, including On the Mat offerings like Yoga (Strength, Mobility) and Pilates from gorgeous locations around the world. Hydrow connects members with an entire community of fellow rowers who experience the rivers and waterways of the world together in synchrony. You, too, can be part of that community. At Hydrow, you’ll have the chance to shape a company that is disrupting the fitness industry while creating engaging content unmatched in the marketplace today. Sound exciting? That’s because it is!

Hourwork

HR Tech

Hourwork

HourWork offers a new, better way to hire and retain hourly workers in today’s understaffed world. Our best-in-class recruitment and retention solutions help match employers with top hourly talent, uncover what matters most to employees, and automatically check in at key milestones to prevent early attrition. Our name is rooted in our commitment to celebrate and build the interdependent relationship between employers and employees. We partner with clients who see themselves as skill providers and who have a deep belief that their business is most successful when their employees feel successful, too. This understanding – coupled with our advanced HourWork technology – differentiates our customers from the abundance of employers ready to hire today as an employer of choice.

Paperless Parts Inc

Manufacturing

Paperless Parts Inc

Paperless Parts is a Boston-based Series B SaaS company backed by OpenView leading the digital transformation for custom part manufacturers. Our cloud-based software helps manufacturers increase revenue and win more business. Paperless Parts' patented technology and proprietary geometry engine unlock hidden insights that enable job shop manufacturers to modernize and grow their businesses. Paperless Parts integrates with your ERP system to level up how you quote and communicate with customers by rapidly pinpointing manufacturability issues, creating quotes, and processing orders for additive manufacturing, sheet metal fabrication, and CNC machining production processes.

Galy

Biotech

Galy

GALY is growing the future.We are an army of dreamers that believe scientists are artists of a new era. We are envisioning a world where we can still produce sought-after materials without the physical turmoil we place on disadvantaged people and the planet. That is why we are revolutionizing the way we produce goods today and therefore sparking a much more sustainable form of doing agriculture.However, nobody takes innovation seriously until you scale it. We are on it! By developing intelligent scale-up strategies with cotton cells, as the in-vitro cotton production market has never been done on an industrial scale, we are capable of doing something truly new. With this mind, we gather a team of highly diverse subjects, ranging from genetic engineering, plant cell culture, bioreactor development, mathematics, statistics, designers, high-performance automation, stylists, illustrators, creative business development, marketing and branding strategies. A group with a strong sense of purpose on a mission to find ways to save our planet.

Details

Go to Directory

Latest News

Dive into our blog for the latest trends and success stories from the Boston's startup community.

July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.