Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Emulate

Healthcare

Emulate

Emulate Inc. is a privately held company that creates advanced in vitro models for understanding how diseases, medicines, chemicals, and foods affect human health. Our lab-ready Human Emulation System® includes three components: Zoë® Culture Module, Organ-Chips, and analytical software applications. The platform provides a window into the inner workings of human biology and disease—offering researchers a new technology designed to predict human response with greater precision and detail than conventional cell culture or animal-based experimental testing. Research conducted using our Organ-Chips has been published in high-impact scientific journals, including Science. In addition, Organ-Chips have been acquired by the Museum of Modern Art (MoMA) in New York for their permanent collection and have also been awarded Product Design of the Year 2015 by London’s Design Museum.

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UBERDOC

Healthcare

UBERDOC

"Patient choice is the cornerstone of our mission because it strengthens the doctor-patient relationship. When patients are free to choose their doctor, it puts the control back where it belongs, and no patient should ever have to be denied access to the care they need because of insurance restrictions or cost. UBERDOC is built by those on the front lines of medicine to give patients a simpler solution."

Ascend Elements

Chemicals

Ascend Elements

Ascend Elements is an independent manufacturer of advanced battery materials using valuable elements reclaimed from spent lithium-ion batteries. Their patented Hydro-to-Cathode® direct precursor synthesis process transforms today’s waste into high-value materials for tomorrow’s EV batteries — a giant step up in sustainability for the entire industry.

BlockJoy

Blockchain

BlockJoy

BlockJoy allows you to deploy and run your own blockchain nodes on any infrastructure you choose. It started as a project to manager staking with friends and family. We built advanced tooling to optimize validator management for teams of two. But, due to the sheer difficulty of installing and running nodes, our little VaaS company grew crazy fast. We quickly realized that VaaS can’t work for a network because it centralizes control. We turned our platform into a SaaS tool so that anyone could launch and run their own node with full control over where and on what infrastructure it runs. Now, network operators can run their own nodes; BlockJoy just takes the headaches away.

1upHealth

Healthcare

1upHealth

1upHealth provides the healthcare industry’s most sophisticated FHIR-enabled health data platform for claims and clinical data acquisition, exchange, and compute. From leading health plans and state Medicaid agencies to innovative digital health organizations and top performing ACOs, over 75 health organizations rely on 1upHealth to meet evolving regulatory requirements and optimize claims and clinical data-driven initiatives. With the push towards digital quality measures, population health analytics, value-based contracts, and better healthcare experiences, the 1up managed platform helps our customers to meet the growing demands for data access and connectivity.

Piaggio Fast Forward

Automotive

Piaggio Fast Forward

Piaggio Fast Forward is a new technology and design company established in 2015 by the Piaggio Group, the manufacturers of Vespa, Aprilia, Moto Guzzi, Derbi, and Gilera. PFF was established with an open mandate to re-think smart mobility platforms in a world where city navigation and short-distance transportation are rapidly changing. We’re a highly creative, motivated, interdisciplinary team of innovators committed to building lightweight, semi-autonomous, and entirely self-driving mobility platforms that easily, safely, and efficiently move people and goods in urban settings

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Latest News

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.