Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Gradient AI

Insurtech

Gradient AI

Gradient AI was founded in order to address the need for state-of-the-art Artificial Intelligence (AI) and Machine Learning (ML) solutions for the trillion-dollar insurance industry. Our software-as-a-service platform uses AI to help commercial insurers automate and improve underwriting results, reduce claim costs, and improve operational efficiencies. Our software and models are utilized by many of the world’s most recognized Insurance Carriers, MGAs, TPAs, Pools, PEOs and more. Our team of expert Data Scientists and Insurance Technology experts have an exceptional history of building wildly successful insurance technology companies, with the most satisfied customers in the industry. At GradientAI we focus exclusively on delivering measurable results for your underwriting and claims operations.

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Zus Health

Healthcare

Zus Health

Zus is the only shared health data platform designed to accelerate healthcare data interoperability by providing easy-to-use patient data at the point of care via API, embedded components, and direct EHR integrations. Our mission is to catalyze healthcare's greatest inventors by maximizing the value of patient insights - so that they can build up, not around.

Iterative Health

Healthcare

Iterative Health

Iterative Health is pioneering the use of artificial intelligence-based precision medicine in gastroenterology (GI), with the aim of helping to optimize clinical trials investigating treatment of inflammatory bowel disease (IBD). We use advanced machine learning and computer vision to interpret endoscopic images along with other types of data, helping clinicians to better assess patients with potential GI problems. This gives practitioners enhanced capabilities in the detection, annotation, disease scoring and treatment of GI related diseases. Iterative Health is initially applying these advances towards standardizing disease severity characterization for inflammatory bowel disease. Ultimately, the company aims to establish more meaningful endpoints to serve as better predictors of both therapeutic response and disease outcomes. The company is headquartered in Cambridge, Massachusetts.

Silvertree

Consumer

Silvertree

Silvertree is on a mission to inspire the world’s aging population. We are developing a wellness wearable platform that provides the right balance of safety, connection, and style for active older adults. Aging is a personal experience, yet aging with dignity and independence so often includes the caring involvement of family and loved ones. That is why we are designing a stylish, wrist-worn wearable that is built for safety and deeply rooted in human connection, across generations. We aim to be the consumer brand associated with vitality, style, and independence for the growing population of fifty-five million Americans ages sixty-five and beyond.

JellyFish

Software

JellyFish

Jellyfish is the pioneer Engineering Management Platform that enables engineering leaders to align engineering work with strategic business objectives. By analyzing engineering signals and contextual business data, Jellyfish provides complete visibility into engineering organizations, the work they do, and how they operate. Companies like SessionM (A Mastercard Company) and Toast use Jellyfish to optimize the allocation of engineering resources to focus their teams on what matters most to the business.

Spoiler Alert

Software

Spoiler Alert

Transforming excess inventory from a problem into a profit. Spoiler Alert is a B2B sales software company helping CPG manufacturers and distributors to manage excess and slow-moving inventory by digitizing the liquidation process. Our goal is to help our customers recover value for products that otherwise would be wasted, allowing them to increase profits, strengthen customer relationships, increase the effectiveness of supply chain managers, and allow for more accurate demand planning. Founded by alumni of MIT, Spoiler Alert works with some of the world's largest companies, including Campbell Soup Company, Danone North America, HelloFresh, KeHE Distributors, Kraft Heinz, Mondelēz, Johnsonville, and Nestlé, along with a growing network of discount channels committed to increasing affordable food access.

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Latest News

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.