Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Mainstay

At Mainstay, we believe one conversation can spark a brighter future. Our Engagement Platform makes it easy for colleges and businesses to start and measure conversations that drive action at scale. From our rigorous research methods to our Behavioral Intelligence framework — everything we do is designed to help people take the next step toward achieving their goals.

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Hydrow

Healthcare

Hydrow

New to the market, fast-growing, incredibly innovative, and already recognized as one of the Boston Globe’s Top Places to Work, Hydrow is the Live Outdoor Reality (LOR)™ rowing machine that delivers on-water experiences at home with workouts led by world-class athletes. Engaging twice as many muscles as cycling (86%, in fact), Hydrow’s interactive technology delivers challenging virtual workouts, including On the Mat offerings like Yoga (Strength, Mobility) and Pilates from gorgeous locations around the world. Hydrow connects members with an entire community of fellow rowers who experience the rivers and waterways of the world together in synchrony. You, too, can be part of that community. At Hydrow, you’ll have the chance to shape a company that is disrupting the fitness industry while creating engaging content unmatched in the marketplace today. Sound exciting? That’s because it is!

Entrada Therapeutics

Biotech

Entrada Therapeutics

Headquartered in Boston’s Seaport community, Entrada Therapeutics is a growing biopharmaceutical company innovating to transform the treatment of devastating diseases through intracellular therapeutics. We’re establishing a new class of medicines, Endosomal Escape Vehicles (EEV™), with the potential to engage intracellular targets that have long been considered inaccessible and undruggable. Our EEV™ therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues with an improved therapeutic index.

BlockJoy

Blockchain

BlockJoy

BlockJoy allows you to deploy and run your own blockchain nodes on any infrastructure you choose. It started as a project to manager staking with friends and family. We built advanced tooling to optimize validator management for teams of two. But, due to the sheer difficulty of installing and running nodes, our little VaaS company grew crazy fast. We quickly realized that VaaS can’t work for a network because it centralizes control. We turned our platform into a SaaS tool so that anyone could launch and run their own node with full control over where and on what infrastructure it runs. Now, network operators can run their own nodes; BlockJoy just takes the headaches away.

Dispense

eCommerce

Dispense

Dispensaries know their customers better than anyone. Dispensary software should give them the flexibility and control needed to make the right decisions and offer exceptional service. Dispense provides cannabis businesses with simple-to-use tools to boost sales and manage operations - on your own terms. The eCommerce software empowers dispensaries to sell online, increase traffic, build customer relationships, and scale businesses. And with our customizable dispensary management functionality, everything integrates easily into your specific operation. Dispense is not a marketplace; you always own your data, so your efforts never benefit your competitors. That means better customer relationships and more online visibility.

HqO

Real Estate

HqO

HqO is transforming how people connect with each other and the places they work. The HqO Workplace Experience Platform makes it easy for companies and commercial property teams to create modern workplaces through world-class amenities and services that allow people to thrive and do their best work. Active in over 200 million square feet in 25 countries, 57% of the Fortune 100 rely on HqO to enhance their workplace experiences, improve employee satisfaction, and drive operational excellence.

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Latest News

Dive into our blog for the latest trends and success stories from the Boston's startup community.

July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.