Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Descrybe.ai

descrybe.ai is a singular way to search for, and understand, caselaw. Our unique process leverages generative AI to make complex legal information more accessible to professionals and laypeople alike. We are laser-focused on easy access to caselaw research, by lowering cost (it's free!), increasing ease of use, and employing natural language search and summarization capacity.

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BIY China

Software

Education

BIY China

Build-It-Yourself offers an art and engineering program driven by technology-in-education research at MIT. Our mission is to inspire and guide the next generation of builders to use technology creatively in a unique global laboratory.

Cellino

Biotech

Cellino

Cellino is building a scalable, automated biomanufacturing system for potentially curative personalized cell therapies. Cellino’s vision is to enable healthier lives worldwide with personalized treatments derived from induced pluripotent stem cells (iPSCs), which can serve as the basis for therapies for a host of chronic degenerative diseases, including vision loss and Parkinson's disease.

Soofa

Software

Soofa

Founded in 2014 out of the MIT media lab, sustainable Soofa Signs are the leading solar-powered communication tool for cities and advertisers. Currently, Soofa Signs has homes in over 57 cities across the U.S. with plans to expand. Soofa advertisers are guaranteed high traffic, unique locations, countless ways to measure success, and a platform to update messaging in real time. We’ve worked with brands large and small like Harpoon, RedBull, New England Revolution, and Wayfair, proving that more businesses are emphasizing sustainable advertising practices. Additionally, cities like Boston, Atlanta, and Miami utilize Soofa Signs to create unique and engaging messaging with their communities thanks to our neighborhood news feed. If it’s an urgent message, or one just for fun, Soofa Signs make it easy to get information to your intended audience.

Asimov

Biotech

Asimov

Headquartered in Boston, Asimov's mission is to advance humanity's ability to design living systems, enabling biotechnologies with outsized societal benefit. The company is developing a synthetic biology platform – from cells to software – to design and manufacture next-generation therapeutics, including biologics, cell/gene therapies, and RNA. Founded by bioengineers from MIT and Boston University, the company has raised over $200 million from top institutional investors including Andreessen Horowitz, CPP Investments, Horizons Ventures, and Fidelity Management & Research Company. Asimov builds tools to program living cells. By integrating mammalian synthetic biology, computer-aided design, and machine learning, our multi-disciplinary team is advancing the design and manufacture of biologics and gene therapies.

Paperless Parts Inc

Manufacturing

Paperless Parts Inc

Paperless Parts is a Boston-based Series B SaaS company backed by OpenView leading the digital transformation for custom part manufacturers. Our cloud-based software helps manufacturers increase revenue and win more business. Paperless Parts' patented technology and proprietary geometry engine unlock hidden insights that enable job shop manufacturers to modernize and grow their businesses. Paperless Parts integrates with your ERP system to level up how you quote and communicate with customers by rapidly pinpointing manufacturability issues, creating quotes, and processing orders for additive manufacturing, sheet metal fabrication, and CNC machining production processes.

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Latest News

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.