Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Flipside Crypto

FinTech

Flipside Crypto

Flipside enables blockchains to live up to their full potential, by decoding and explaining blockchain behaviors. Our proprietary process extracts all of the data from blockchains and applies labels to transactions in order to identify and understand on-chain behaviors. The data is then streamed into our Business Intelligence Dashboards, to provide a clear view of real-time stakeholder behaviors and all asset flows. Flipside provides analytics to more than 80 cryptocurrency organizations and distributes ratings products via partners such as CoinMarketCap, Messari, MarketWatch and TheStreet. Flipside Crypto is backed by True Ventures, Founder Collective, CoinBase Ventures, Digital Currency Group, Galaxy Digital, and other investors.

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Descrybe.ai

descrybe.ai is a singular way to search for, and understand, caselaw. Our unique process leverages generative AI to make complex legal information more accessible to professionals and laypeople alike. We are laser-focused on easy access to caselaw research, by lowering cost (it's free!), increasing ease of use, and employing natural language search and summarization capacity.

Silvertree

Consumer

Silvertree

Silvertree is on a mission to inspire the world’s aging population. We are developing a wellness wearable platform that provides the right balance of safety, connection, and style for active older adults. Aging is a personal experience, yet aging with dignity and independence so often includes the caring involvement of family and loved ones. That is why we are designing a stylish, wrist-worn wearable that is built for safety and deeply rooted in human connection, across generations. We aim to be the consumer brand associated with vitality, style, and independence for the growing population of fifty-five million Americans ages sixty-five and beyond.

Emulate

Healthcare

Emulate

Emulate Inc. is a privately held company that creates advanced in vitro models for understanding how diseases, medicines, chemicals, and foods affect human health. Our lab-ready Human Emulation System® includes three components: Zoë® Culture Module, Organ-Chips, and analytical software applications. The platform provides a window into the inner workings of human biology and disease—offering researchers a new technology designed to predict human response with greater precision and detail than conventional cell culture or animal-based experimental testing. Research conducted using our Organ-Chips has been published in high-impact scientific journals, including Science. In addition, Organ-Chips have been acquired by the Museum of Modern Art (MoMA) in New York for their permanent collection and have also been awarded Product Design of the Year 2015 by London’s Design Museum.

Spoiler Alert

Software

Spoiler Alert

Transforming excess inventory from a problem into a profit. Spoiler Alert is a B2B sales software company helping CPG manufacturers and distributors to manage excess and slow-moving inventory by digitizing the liquidation process. Our goal is to help our customers recover value for products that otherwise would be wasted, allowing them to increase profits, strengthen customer relationships, increase the effectiveness of supply chain managers, and allow for more accurate demand planning. Founded by alumni of MIT, Spoiler Alert works with some of the world's largest companies, including Campbell Soup Company, Danone North America, HelloFresh, KeHE Distributors, Kraft Heinz, Mondelēz, Johnsonville, and Nestlé, along with a growing network of discount channels committed to increasing affordable food access.

Appcues

Software

No-Code

Appcues

Appcues makes it easy to measure and improve product adoption—without a developer. The no-code platform empowers non-technical teams to track and analyze product usage, and publish beautiful in-app onboarding tours, announcements, and surveys, in minutes. Appcues is trusted by thousands of innovative product-led businesses around the world, including Amplitude, Yotpo, Pluralsight, MongoDB, Codepen, and SquareSpace. True to form, Appcues also makes it easy to get started.

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.