Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Emulate

Healthcare

Emulate

Emulate Inc. is a privately held company that creates advanced in vitro models for understanding how diseases, medicines, chemicals, and foods affect human health. Our lab-ready Human Emulation System® includes three components: Zoë® Culture Module, Organ-Chips, and analytical software applications. The platform provides a window into the inner workings of human biology and disease—offering researchers a new technology designed to predict human response with greater precision and detail than conventional cell culture or animal-based experimental testing. Research conducted using our Organ-Chips has been published in high-impact scientific journals, including Science. In addition, Organ-Chips have been acquired by the Museum of Modern Art (MoMA) in New York for their permanent collection and have also been awarded Product Design of the Year 2015 by London’s Design Museum.

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SparkCharge

Automotive

SparkCharge

SparkCharge is at the vanguard of mobile electric vehicle (EV) charging solutions, aiming to redefine the way businesses and individuals think about EV charging. With a vision to make EV charging more accessible and convenient, SparkCharge offers innovative solutions that eliminate the need for traditional fixed charging infrastructure. Their flagship product, the Roadie Portable, is a mobile DC fast charger designed for immediate deployment, offering grid-free, modular, and customizable charging solutions. In addition to hardware, SparkCharge introduces Charging-as-a-Service (CaaS) programs, providing businesses with turnkey EV charging solutions without the hassles of installation, permitting, or upfront costs. This service ensures 99.9% charger uptime and can be deployed in as little as 14 days. As EV sales surge and businesses transition to greener fleets, SparkCharge is a beacon of innovation, offering cost-effective, flexible, and scalable EV charging solutions. With a commitment to leading the charge in the EV revolution, SparkCharge is not just offering products but shaping the future of electric vehicle charging.

Stavvy

Software

Stavvy

Stavvy helps real estate professionals grow their business and ditch the paper process. The Stavvy platform makes it easy for you to work and collaborate with lending, title/settlement, notarial, and loan servicing partners. Together in one secure platform, you’ll have the tools to boost productivity and dismantle communication silos. Our feature line includes must-have tools like eSign, RON, eRecording, digital audit trail, and a proprietary Eligibility Engine. Recognized for its innovation, Stavvy has played a pivotal role in digital real estate closings, making processes more cost-effective and efficient for all stakeholders involved. As the real estate industry continues to evolve, Stavvy stands as a beacon of digital transformation, ensuring seamless transactions and heightened customer satisfaction.

Provengo

SaaS

Software Development

Provengo

We develop tools for system specification, validation, and correct-by-construction workflow automation, based on groundbreaking - yet friendly - formal methods.

Flipside Crypto

FinTech

Flipside Crypto

Flipside enables blockchains to live up to their full potential, by decoding and explaining blockchain behaviors. Our proprietary process extracts all of the data from blockchains and applies labels to transactions in order to identify and understand on-chain behaviors. The data is then streamed into our Business Intelligence Dashboards, to provide a clear view of real-time stakeholder behaviors and all asset flows. Flipside provides analytics to more than 80 cryptocurrency organizations and distributes ratings products via partners such as CoinMarketCap, Messari, MarketWatch and TheStreet. Flipside Crypto is backed by True Ventures, Founder Collective, CoinBase Ventures, Digital Currency Group, Galaxy Digital, and other investors.

Entrada Therapeutics

Biotech

Entrada Therapeutics

Headquartered in Boston’s Seaport community, Entrada Therapeutics is a growing biopharmaceutical company innovating to transform the treatment of devastating diseases through intracellular therapeutics. We’re establishing a new class of medicines, Endosomal Escape Vehicles (EEV™), with the potential to engage intracellular targets that have long been considered inaccessible and undruggable. Our EEV™ therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues with an improved therapeutic index.

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.