Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Morphoceuticals

Biotech

Morphoceuticals

Morphoceuticals targets native bioelectrical and biochemical pathways to develop novel therapies that access core aspects of our biological operating system. Building on our success regenerating functioning limbs using topical administration of ion channel modulators, we aim to achieve transformative therapeutic outcomes by leveraging computational control of our bioelectric programming, and triggering developmental pathways too complex to micromanage.

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Entrada Therapeutics

Biotech

Entrada Therapeutics

Headquartered in Boston’s Seaport community, Entrada Therapeutics is a growing biopharmaceutical company innovating to transform the treatment of devastating diseases through intracellular therapeutics. We’re establishing a new class of medicines, Endosomal Escape Vehicles (EEV™), with the potential to engage intracellular targets that have long been considered inaccessible and undruggable. Our EEV™ therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues with an improved therapeutic index.

Rezonate

Software

Rezonate

Rezonate.io is a cutting-edge Identity Centric Security Platform designed to fortify both human and machine identities against cyber threats throughout their entire access journey to business assets. With a bold proclamation that "A/B Testing is Dead," Rezonate.io champions a shift from traditional methods to AI-driven solutions. Their platform offers comprehensive features such as real-time monitoring of privileges and activities, risk reduction, and active threat mitigation. Recognized as a "Cool Vendor" in the 2023 Gartner® Cool Vendors™ in Identity-First Security report, Rezonate.io is committed to delivering an all-encompassing identity-first security platform that bolsters security posture, fortifies defense mechanisms, and facilitates effective threat remediation. Rezonate.io's platform is uniquely designed to discover, profile, and protect identities, ensuring secure access to cloud infrastructure and critical SaaS applications. It provides continuous exposure reduction by uncovering and rectifying weak authentication, misconfigured trust relations, and other vulnerabilities. Moreover, the platform's adaptive access engine optimizes security controls, ensuring that identities are managed efficiently.

Electra Vehicles

Automotive

Electra Vehicles

Electra Vehicles is an industry leader in AI software for improved battery lifetime, range, and safety. Electra offers active embedded battery pack controls, electric fleet analytics, and design simulation software to address the challenges behind electrification in the automotive industry and beyond. Electra was co-founded in 2015 by Fabrizio Martini, who came to the idea while working as a Principal Investigator on a NASA project. With the latest in Machine Learning and access to over 300 cell models for simulation, Electra is equipped to enable current battery pack technology and support battery innovation for the future. Contact Electra for details about our AI solutions to the e-Mobility market's most pressing issues.

Overjet

Overjet is pioneering the next era of dentistry. Modern DSOs and insurance companies are realizing the clinical and operational value of innovative technologies and moving towards smart operations that leverage artificial intelligence. Guided by a patient-centric AI, Overjet’s FDA-cleared platform offers more data points in x-rays than previously possible. It integrates with major practice management and imaging systems to guide clinicians to arrive at precise & accurate diagnostic decisions, better care and patient outcomes that drive dentistry forward. With data-driven diagnoses being the key to success, Overjet enables clinicians to achieve higher clinical accuracy, precision, and consistency. When dentists see objective confirmation of a diagnosis they made, they feel more confident, and patients know they can trust their doctors. Building on formative experiences with MIT and Harvard School of Dental Medicine, Overjet was founded on the vision to enhance clinical decision-making to improve oral health. Every day, some of the largest DSOs, dental groups, and insurance companies rely on accurate information provided by Overjet to deliver care and services.

Soofa

Software

Soofa

Founded in 2014 out of the MIT media lab, sustainable Soofa Signs are the leading solar-powered communication tool for cities and advertisers. Currently, Soofa Signs has homes in over 57 cities across the U.S. with plans to expand. Soofa advertisers are guaranteed high traffic, unique locations, countless ways to measure success, and a platform to update messaging in real time. We’ve worked with brands large and small like Harpoon, RedBull, New England Revolution, and Wayfair, proving that more businesses are emphasizing sustainable advertising practices. Additionally, cities like Boston, Atlanta, and Miami utilize Soofa Signs to create unique and engaging messaging with their communities thanks to our neighborhood news feed. If it’s an urgent message, or one just for fun, Soofa Signs make it easy to get information to your intended audience.

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Latest News

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.