Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

Join Discover

Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

FreezeNit

Healthcare

FreezeNit

FreezeNit will improve the treatment of head lice for millions of families in the US. Our innovative approach simultaneously freezes and asphyxiates lice using only cold CO2 gas, in one short, non-toxic treatment.

Details

Mainstay

At Mainstay, we believe one conversation can spark a brighter future. Our Engagement Platform makes it easy for colleges and businesses to start and measure conversations that drive action at scale. From our rigorous research methods to our Behavioral Intelligence framework — everything we do is designed to help people take the next step toward achieving their goals.

1upHealth

Healthcare

1upHealth

1upHealth provides the healthcare industry’s most sophisticated FHIR-enabled health data platform for claims and clinical data acquisition, exchange, and compute. From leading health plans and state Medicaid agencies to innovative digital health organizations and top performing ACOs, over 75 health organizations rely on 1upHealth to meet evolving regulatory requirements and optimize claims and clinical data-driven initiatives. With the push towards digital quality measures, population health analytics, value-based contracts, and better healthcare experiences, the 1up managed platform helps our customers to meet the growing demands for data access and connectivity.

Reprise

Software

Reprise

Reprise empowers enterprise sales and marketing teams to build personalized, interactive demos that lead to greater conversions, shorter sales cycles, and more revenue. For sales and marketing leaders who strive to expertly showcase their products, Reprise is the only enterprise-class demo creation platform that fully integrates live demos, guided demos, and product tours to seamlessly show the value of your product at every phase of the buyer's journey. Launched in 2020, Reprise has been recognized as a leader in G2's winter 2023 report of best Mid-Market Content Experience Platforms. Backed by ICONIQ Growth, Bain Capital Ventures, Accomplice VC, and Glasswing Ventures, Reprise is changing how companies deliver demos.

Human Cloud

Cloud

Human Cloud

We help companies find the best flexible talent solutions so that they can scale their flexible workforce. We spent 10+ years building the largest Knowledge Graph for the flexible talent industry, then launched the Human Cloud Platform, a platform that helps companies find, vet, and deploy the perfect flexible talent solution. We also built the #1 global media channel in the flexible workforce category (top 10% global podcast), published the Human Cloud Book with HarperCollins, and reached 120,000+ executives weekly. Want to get involved? Find your perfect solution at App.HumanCloud.com

Laudio

Healthcare

Laudio

Laudio empowers frontline healthcare leaders at health systems to drive outcomes that matter. With its intelligent leadership solution, Laudio automates repetitive work and serves up daily recommendations and best practices that help frontline leaders gain better visibility into their teams, find opportunities for meaningful connection, and discover clearer paths to achieving their goals. Today, forward-thinking leaders across health systems use Laudio to improve productivity, employee engagement, and patient care.

Details

Go to Directory

Latest News

Dive into our blog for the latest trends and success stories from the Boston's startup community.

July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.