Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

FreezeNit

Healthcare

FreezeNit

FreezeNit will improve the treatment of head lice for millions of families in the US. Our innovative approach simultaneously freezes and asphyxiates lice using only cold CO2 gas, in one short, non-toxic treatment.

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Hourwork

HR Tech

Hourwork

HourWork offers a new, better way to hire and retain hourly workers in today’s understaffed world. Our best-in-class recruitment and retention solutions help match employers with top hourly talent, uncover what matters most to employees, and automatically check in at key milestones to prevent early attrition. Our name is rooted in our commitment to celebrate and build the interdependent relationship between employers and employees. We partner with clients who see themselves as skill providers and who have a deep belief that their business is most successful when their employees feel successful, too. This understanding – coupled with our advanced HourWork technology – differentiates our customers from the abundance of employers ready to hire today as an employer of choice.

Filtered.ai

HR Tech

Filtered.ai

Filtered.AI is a cutting-edge hiring platform that empowers leading brands to harness the power of generative AI in the recruitment process. With a focus on verifying skills and streamlining interviews, Filtered.AI ensures that every candidate is the best fit for the role every time. The platform offers a comprehensive Skills Verification Platform that aids hiring teams in authenticating, assessing, interviewing, and selecting the most suitable candidates for any given role. By leveraging advanced AI solutions, Filtered.AI provides features such as government ID checks for candidate identity verification, AI-powered fraud monitoring, objective technical skill assessments tailored for each role, and AI-assisted interviews that offer richer insights. Furthermore, the platform emphasizes objective data delivery to Diversity, Equity, and Inclusion (DEI) programs, offering anonymous candidate performance reviews and AI-driven insights to minimize bias and enhance DEI outcomes at scale. With a commitment to providing a seamless candidate experience, Filtered.AI boasts a 92% candidate satisfaction rate. Prioritizing data privacy and security, the platform ensures GDPR compliance, strict security protocols, and responsible data management. Serving global customers and candidates across 100+ countries, Filtered.AI is redefining the future of hiring, combining technology and human insight to create a more efficient and unbiased recruitment process.

Morphoceuticals

Biotech

Morphoceuticals

Morphoceuticals targets native bioelectrical and biochemical pathways to develop novel therapies that access core aspects of our biological operating system. Building on our success regenerating functioning limbs using topical administration of ion channel modulators, we aim to achieve transformative therapeutic outcomes by leveraging computational control of our bioelectric programming, and triggering developmental pathways too complex to micromanage.

Entrada Therapeutics

Biotech

Entrada Therapeutics

Headquartered in Boston’s Seaport community, Entrada Therapeutics is a growing biopharmaceutical company innovating to transform the treatment of devastating diseases through intracellular therapeutics. We’re establishing a new class of medicines, Endosomal Escape Vehicles (EEV™), with the potential to engage intracellular targets that have long been considered inaccessible and undruggable. Our EEV™ therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues with an improved therapeutic index.

Emulate

Healthcare

Emulate

Emulate Inc. is a privately held company that creates advanced in vitro models for understanding how diseases, medicines, chemicals, and foods affect human health. Our lab-ready Human Emulation System® includes three components: Zoë® Culture Module, Organ-Chips, and analytical software applications. The platform provides a window into the inner workings of human biology and disease—offering researchers a new technology designed to predict human response with greater precision and detail than conventional cell culture or animal-based experimental testing. Research conducted using our Organ-Chips has been published in high-impact scientific journals, including Science. In addition, Organ-Chips have been acquired by the Museum of Modern Art (MoMA) in New York for their permanent collection and have also been awarded Product Design of the Year 2015 by London’s Design Museum.

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Latest News

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.