Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Iterative Health

Healthcare

Iterative Health

Iterative Health is pioneering the use of artificial intelligence-based precision medicine in gastroenterology (GI), with the aim of helping to optimize clinical trials investigating treatment of inflammatory bowel disease (IBD). We use advanced machine learning and computer vision to interpret endoscopic images along with other types of data, helping clinicians to better assess patients with potential GI problems. This gives practitioners enhanced capabilities in the detection, annotation, disease scoring and treatment of GI related diseases. Iterative Health is initially applying these advances towards standardizing disease severity characterization for inflammatory bowel disease. Ultimately, the company aims to establish more meaningful endpoints to serve as better predictors of both therapeutic response and disease outcomes. The company is headquartered in Cambridge, Massachusetts.

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Mainstay

At Mainstay, we believe one conversation can spark a brighter future. Our Engagement Platform makes it easy for colleges and businesses to start and measure conversations that drive action at scale. From our rigorous research methods to our Behavioral Intelligence framework — everything we do is designed to help people take the next step toward achieving their goals.

UNICORN

Healthcare

Consumer

UNICORN

Welcome to Unicorn – the visionary movement that's transforming the landscape of period care, one restroom stall at a time. We're more than just an organization; we're a community committed to promoting health, dignity, and equity. With our innovative, low-profile dispensers, we're making organic tampons and pads readily available in every stall of institutions who share our vision - starting with JPMorgan Chase & Co., the first big bank to adopt our revolutionary concept.

BIY China

Software

Education

BIY China

Build-It-Yourself offers an art and engineering program driven by technology-in-education research at MIT. Our mission is to inspire and guide the next generation of builders to use technology creatively in a unique global laboratory.

Stavvy

Software

Stavvy

Stavvy helps real estate professionals grow their business and ditch the paper process. The Stavvy platform makes it easy for you to work and collaborate with lending, title/settlement, notarial, and loan servicing partners. Together in one secure platform, you’ll have the tools to boost productivity and dismantle communication silos. Our feature line includes must-have tools like eSign, RON, eRecording, digital audit trail, and a proprietary Eligibility Engine. Recognized for its innovation, Stavvy has played a pivotal role in digital real estate closings, making processes more cost-effective and efficient for all stakeholders involved. As the real estate industry continues to evolve, Stavvy stands as a beacon of digital transformation, ensuring seamless transactions and heightened customer satisfaction.

Soofa

Software

Soofa

Founded in 2014 out of the MIT media lab, sustainable Soofa Signs are the leading solar-powered communication tool for cities and advertisers. Currently, Soofa Signs has homes in over 57 cities across the U.S. with plans to expand. Soofa advertisers are guaranteed high traffic, unique locations, countless ways to measure success, and a platform to update messaging in real time. We’ve worked with brands large and small like Harpoon, RedBull, New England Revolution, and Wayfair, proving that more businesses are emphasizing sustainable advertising practices. Additionally, cities like Boston, Atlanta, and Miami utilize Soofa Signs to create unique and engaging messaging with their communities thanks to our neighborhood news feed. If it’s an urgent message, or one just for fun, Soofa Signs make it easy to get information to your intended audience.

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Latest News

Dive into our blog for the latest trends and success stories from the Boston's startup community.

July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.